Adrenodoxin , ADX，Ferredoxin（ADX）

(Adrenal) Cortical ferredoxin (adrenodoxin, ADX) is a non-heme iron-sulfur protein in the mitochondria of the adrenal cortex. With a molecular weight of approximately 22,000, it functions in a non-phosphorylated electron transport system and is an electron carrier protein. In the adrenal cortex mitochondria, involved in the biosynthesis of steroid hormones.

 

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The protein is brown, with maximum absorption at 415 nm and 453 nm. It can be reduced by NADPH and flavoenase, and can be oxidized by P-450. It is related to the hydroxylation reaction of steroids caused by oxygen molecules in the adrenal cortex.

 

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In the process of cytochrome P450scc catalyzing the hydroxylation of C-22 and C-20 positions in the cholesterol structure, and then cleaving the carbon chain between them to form pregnenolone, two pairs of electrons are passed by NADPH in each catalytic step. Cortical ferredoxin and its reductase are transported to cytochrome P450scc.

 

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Our company's (adrenal gland) cortical ferredoxin is a genetically recombinant product and does not contain animal-derived viruses. The product has high purity and good activity.

 

 

Source: Gene recombinant expression

 

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Molecular weight: 22 kDa (SDS-PAGE detection)

 

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Purity: ≥90% (SDS-PAGE detection)

 

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Storage conditions: freeze-dried powder stored at 4℃ or long-term storage at -20℃

 

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Transportation conditions: low temperature ice pack

 

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Safety Tips: Not for human experimentation

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