Heart Fatty Acid-Binding Protein Ab（HFABP-Ab）

Heart-shaped fatty acid binding protein (HFABP, also known as FABP3) consists of 132 amino acids and has a molecular weight of 15 kDa. It is one of the most abundant proteins in the heart. hFABP binds two fatty acid molecules and participates in the transport of fatty acyl-CoA, active in the oxidation process, thereby generating energy in the mitochondria.

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Heart-type fatty acid binding protein (HFABP) is a novel small cytoplasmic protein abundant in the heart. It is highly cardiac specific (that is, expressed primarily in cardiac tissue), but is also expressed at low concentrations in tissues other than the heart. After myocardial ischemic injury occurs, HFABP can be found in the blood as early as 1-3 hours after the onset of chest pain, reaching a peak value at 6-8 hours and plasma levels return to normal within 24-30 hours. Therefore HFABP is regarded as a useful biomarker for early diagnosis of myocardial injury.

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Elevated levels of free plasma myoglobin are a widely accepted marker of early myocardial injury and have been shown to exclude acute myocardial infarction within 3-6 hours of symptom onset compared to elevated levels of CK-MB and cTnT. (AMI). But HFABP is more heart-specific and is considered a more accurate diagnostic test because of its biological properties.

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Furthermore, human HFABP can be used as a good biomarker for myocardial infarction detection with high sensitivity and detection rate.

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Our company's HFABP antibodies have high titers and can be directly used in the development or production of HFABP detection reagents.

Source: Rabbit, polyclonal antibody

Purification method: Protein A affinity purification

Titer: 1:1 million

Buffer composition: PBS, 0.1% preservative

Storage conditions: It can be stored for one year at 4℃ and two years at -20℃ (it is recommended to store in separate packages and try to avoid repeated freezing and thawing)

Safety Tips: Not for human experimentation