Fructosylvaline

Glycated hemoglobin in the blood reflects the blood sugar level in the body over a period of time and has been used as an important indicator for the diagnosis and treatment of diabetes in recent years. Currently, enzymatic methods are mainly used on the market to detect the content of glycated hemoglobin in the human body. Using this method to measure glycated hemoglobin requires the use of a special type of enzyme - fructose valine oxidase, which acts on glycated polypeptides or glycated amino acids. , its action product undergoes a series of redox reactions, and finally the content of glycated hemoglobin is determined through the color development of the final product. Therefore, fructose valine oxidase is a key enzyme in the determination of glycated hemoglobin.

Current research shows that the glycosylation site of glycated hemoglobin in human blood is the valine-NH2 residue. Therefore, a simulated substrate for glycated hemoglobin in human blood is prepared, namely fructose-valine [N-(1-deoxy-D- Fructose-1-yl)-valine] is particularly important for screening high activity, high stability and high specificity fructose valine oxidase and studying its enzymatic properties.

Cat# Abt-C-1001

CAS number: 10003-64-2

Molecular formula: C11H21NO7

Relative molecular mass: 279.29

Storage conditions: long-term storage at 2-8°C; dissolve in pure water and pack according to dosage, then freeze at -20°C. Try to avoid repeated freezing and thawing.

Instructions for use: Fructose-valine oxidase catalyzes the reaction of fructose-valine to generate hydrogen peroxide. The hydrogen peroxide causes a color reaction between 4-aminoantipyrine and TBHB under the action of peroxidase.

Safety Tips: This reagent is only used for research and development or production, and is strictly prohibited for human or animal experiments.