Ribonuclease T2（RNASE T2）

RNASE T2 (ribonuclease T2) is an enzyme belonging to the RNase T2 family. It is abundantly expressed in the temporal lobe and fetal brain. The RNASET2 gene is a new member of the extracellular ribonuclease Rh/T2/S-glycoprotein class. It is a single-copy gene located at 6q27, a region on the genetic map that is associated with human malignant tumors and chromosomal rearrangements. Loss of RNASET2 is responsible for leukoencephalopathy, a childhood syndrome of leukoencephalopathy that affects neonatal microcephaly and the development of neurological abnormalities, including psychomotor disorders and epilepsy. Seizures and sensorineural hearing impairment, the brain shows multiple white matter lesions, anterior temporal lobe subcortical cyst walls, myelin dysplasia, ventriculomegaly, and intracranial calcifications.

 

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The RNASET2 provided by our company is a recombinant gene product expressed in mammalian cells. It has high purity, excellent immunogenicity and biological activity.

 

 

Expression host: HEK293 mammalian cells

 

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Source: A DNA sequence encoding the extracellular domain of human RNASET2 (NM_003730.4)

 

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Storage buffer: PBS (pH: 7.4)

 

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Molecular weight: about 36-42 kDa (SDS-PAGE detection)

 

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Purity: ≥95% (SDS-PAGE detection)

 

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Storage conditions: short-term storage at 4°C or long-term storage at -20°C. Try to avoid repeated freezing and thawing.

 

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Transportation conditions: low temperature ice pack

 

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Safety Tips: Not for human experimentati