OX40(CD134;TNFSF4)

OX40 (CD134; TNFSF4) is a member of the TNF superfamily and a type I transmembrane glycoprotein. Human OX40 consists of a 28aa signal peptide, a 185aa extracellular region, a 20aa transmembrane region and a 41aa cytoplasmic region. Human OX40 ligand (OX40L/CD134L) contains 183 amino acids (139 extracellular amino acids, 21 transmembrane amino acids, and 23 intracellular amino acids). It is a member of the TNF family and is a type II transmembrane glycoprotein. OX40/0X40L is a pair of important co-stimulatory molecules that play an important role in the body's immune response and various diseases. Immunotherapy by interfering with their interaction has achieved very good results in many animal models, which provides a basis for It provides a theoretical and experimental basis for future clinical treatments.

​

The OX40-his and OX40-Fc expressed in mammalian cells of our company have high purity and good activity.

​

Human OX40(His tag) OX40(Fc tag)

Cat# Abt-P-4016 a Cat# Abt-P-4016 b

Expression host: HEK293 Expression host: HEK293

Molecular weight: 40-44 kDa Molecular weight: 60-72 kDa

Concentration: 1-2mg/mL Concentration: 1-2mg/mL

Purity: >90% Purity: >90%

Storage environment: 1×PBS (pH7.4) Storage environment: 1×PBS (pH7.4)

Storage conditions: short-term storage at 4℃, long-term storage at -20℃. Avoid repeated freezing and thawing

Safety Tips: Not for human experimentation