Human neutrophil gelatinase-associated apolipoprotein（NGAL）

Neutrophil gelatinase-associated lipocalin (NGAL) is a 25KD glucoprotein and a new member of lipocalin family with a typical β-barrel structure of the family. Based on the recent research, the function of NGAL protein maybe is to protect and regulate the activity of matrix metalloproteinase-9(MMP-9) and to involve in inflammation and innate immunity reaction. NGAL protein also is a novel iron transporter that mediates a new iron delivery pathway. Acute kidney injury(AKI) is a syndrome characterized by loss of function in a short time ( hours to days )．The scarcity of early biomarker for AKI has hindered our ability to launch the therapy for this disease．Neutrophil gelatinase-assocliated lipocalin( NGAL ) is a high efficient clinical biomarker for AKI. At present , Cystatin C is widely used for AKI clinical diagnosis. However, compared to Cystatin C , NGAL diagnosis value for AKI is much higher .

The NGAL provided by our company is the recombinant human protein，with high immunogenicity. it is not only used to immune animal for producing anti-NGAL antibody, which can be used as the core material for the NGAL diagonosis kit, but also can be used as a quality control standard or positive control test.

Product description:

Appearance: White powder, lyophilized or colorless liquid

Preservation solution: PBS, pH7.4

Basic information:

Cat#: Abt-P-2004                         

Source: Recombinant expression

Molecular weight: About 22kDa (SDS-PAGE detection)

Purity: ≥90% (SDS-PAGE test)

Storage: 4℃, store at -20℃ for long-term preservation. Avoid freeze / thaw cycle

Transportation: Cold packs       

Safety tips: Do not use for human experiments