Anti（HSP70 Ab）

Heat shock protein (HSP) is a protein that is induced by various stresses such as damage to the body, cold, ultraviolet exposure, tissue repair, etc. It is related to improving cells' tolerance to damage and stress ability, and exists in In most organisms, it is mainly induced by stimulation of a certain intensity.

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HSP70 is the most abundant heat stress protein among the HSP family proteins. This protein is widely found in animals, plants and microorganisms and plays a "guardian" role. Its main functions are reflected in tolerance of cellular immunity, innate immune response, and resistance to Oxidation, anti-apoptosis and molecular chaperone, HSP70 also participates in and regulates protein folding modifications. The broad distribution and multifunctionality of HSP70 make it one of the most studied stress proteins. HSP70 has a molecular weight of approximately 70kD and is known as the major heat shock protein, including more than 20 proteins with molecular weights of 68, 72, 73, 75, and 78kDa.

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HSP70 family proteins have similar molecular weights, isoelectric points between PH5.2-6.3, and similar trypsin peptide profiles. They are often highly induced in stress cells of almost all organisms and have the function of protecting the body and cells. Under normal circumstances, HSP70 is located in the cytoplasm. When stimulated by heat shock, HSP70 in the nucleus increases rapidly and only a small amount exists in the plasma. When the cell is in the recovery stage, HSP70 in the nucleus disappears, but low-level HSP70 expression remains in the plasma.

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The anti-human HSP70 (RefSeq: NM_005345.5, HSP70-1A, HSP A1A) antibody provided by our company is a rabbit polyclonal antibody, which is a member of the heat shock protein family, HSP70-1A (HSP A1A), with high titer and stability.

Source: Rabbit, polyclonal antibody

Purification method: Protein A affinity purification

Titer: 1: 1 million

Buffer composition: PBS, 0.1% preservative

Storage conditions: It can be stored for one year at 4℃ and two years at -20℃ (it is recommended to store in separate packages and try to avoid repeated freezing and thawing)

Safety Tips: Not for human experimentation