Prostate-Specific Antigen（PSA）

PSA is useful in diagnosing early-stage, asymptomatic prostate cancer. Under normal circumstances, PSA is a serine protease secreted by prostate epithelial cells. It is a glycoprotein that is directly secreted into the prostate duct system. Its normal function is to help hydrolyze and liquefy semen clots, which is related to male fertility. There is a blood-epithelial barrier around the normal prostate duct system, which prevents PSA produced by the prostate epithelium from directly entering the blood, thereby maintaining a low concentration of PSA in the blood. It is generally believed that serum PSA less than 4.0 ng/mL is normal, and PSA greater than 10 ng/mL increases the risk of prostate cancer. When prostate cancer occurs, the blood-epithelial barrier is destroyed, and the cancer secretes more PSA, causing PSA to directly enter the blood. The higher the malignancy of the cancer, the greater the damage to normal prostate tissue, and the PSA in the serum The higher.

Expression host: HEK293

​Molecular weight: 34-36 kDa

Concentration: 1-2mg/mL

Purity: >90%

Storage environment: 1×PBS (pH7.4)

Storage conditions: Store at 4℃ for one month, -20℃ for one year (it is recommended to store in separate packages to avoid repeated freezing and thawing)

Safety Tips: Not for human experimentation